cancer-epigenetics

High Enhancer Activity is an Epigenetic Feature of HPV Negative Atypical Head and Neck Squamous Cell Carcinoma

Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

Chromatin State Dynamics Confers Specific Therapeutic Strategies in Enhancer Subtypes of Colorectal Cancer

Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state

Enhancer reprogramming confers dependence on glycolysis and IGF signaling in KMT2D mutant melanoma

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

Loss of histone acetylation and H3K4 methylation promotes melanocytic malignant transformation