epigenetics

Computational methods to explore chromatin state dynamics

Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

Chromatin State Dynamics Confers Specific Therapeutic Strategies in Enhancer Subtypes of Colorectal Cancer

Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells

Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state

Enhancer reprogramming confers dependence on glycolysis and IGF signaling in KMT2D mutant melanoma

TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes